Skip to main content

Work Begins on Massive TMC3 Project

Published Aug 31, 2021 by A.J. Mistretta

TMC3 Aerial July 2022

Aerial rendering of TMC3

Work has begun on TMC3, the much-anticipated life sciences research and commercialization campus that backers believe will become a robust global nexus for that work in the years to come. 

The Texas Medical Center announced on August 31 that construction has begun on phase one of the 37-acre project, which is backed by $1.8 billion in secured financing. The full TMC3 master plan, set to materialize over several years, spans more than 6 million square feet of development. Officials say TMC3 will result in 42,000 new jobs and an annual economic impact of $5.4 billion. 

Phase one will include 950,000 square feet dedicated to translational research anchored by Boston-based Beacon Capital Partners and its strategic partner Braidwell, a life sciences-focused investment firm. The first phase will also include a 500+ room hotel with more than 650,000 square feet of conference space, a 350-unit residential tower, parking and nearly 19 acres of public space including parks. 

“With more than 100,000 employees, vast intellectual capital and a long-standing patient focus, our capacity for innovation is second to none,” said William McKeon, President & CEO of TMC. “The collective power of TMC’s hospitals and academic institutions has accelerated the pace of scientific discovery for years. TMC3 extends our collaboration to Fortune 100 life sciences companies and entrepreneurial ventures. The impact on patients worldwide has the potential to be nothing short of life-changing.”

TMC3 was designed by Boston-based Elkus Mafredi Architects, which has designed several of Massachusetts’ major life sciences complexes. According to a release from TMC: “The plan emphasizes creative collisions between people, institutions, and ideas, bolstered by a state-of-the-art infrastructure that will support a mix of healthcare, life science and business users. In addition, purposeful, growth focused capital investments will foster an ever-expanding network of business partners, from entrepreneurial ventures to Fortune 100 companies.”

TMC3's founding institutions — the TMC, Baylor College of Medicine, Texas  A&M University Health Science Center, the University of Texas Health Science Center at Houston and the University of Texas M.D. Anderson Cancer Center — will each have their own dedicated facilities on the campus when its complete.

Learn more about TMC3 and life sciences in Houston. 

Related News

Aerospace & Aviation

Houston House Spotlights Tech and Innovation at SXSW

The Greater Houston Partnership hosted Houston House at SXSW, a two-day activation program led by innovation leaders and startup founders, from March 13-14. With over 630 attendees over the two days of programming, Houston House delivered a diverse set of panels discussing venture capital funding, equitable energy transition, commercial aerospace and more! If you didn’t get a chance to attend our panels, here’s a glimpse of the conversations surrounding the advancements happening in Houston. Click to expand Day 1: Sunday, March 13 Funding the Next Generation of Diverse Founders Felix Chevalier., Co-Founder, Urban Capital Network Denise Hamilton, Work Futurist and CEO, WatchHerWork Jesse Martinez, Investment Partner/Venture Partner, Resolved/ VamosVentures Houston House’s kickoff on March 13 offered a space for startups and technology to converge. The big question for startup founders is often “where do I begin?” The answer is funding. The panel discussed how founders can overcome challenges when it comes to securing funding. “For founders, you have to pack your bags and get out there, like SXSW. Walk around the street, go to free shows, or stand at the hotel lobby. The opportunity is out there to meet people to whatever your objective might be.” —Felix Chevalier, Co-Founder of Urban Capital Network “I am a solo founder and I remember I met with multiple technical co-founders, but I was told because ‘you’re a black woman you’ll never be able to raise the money.’” —Denise Hamilton, Work Futurist and CEO of WatchHerWork Despite setbacks, the COVID-19 pandemic has placed startup businesses back on track. “After the pandemic, you eliminate the geographical boundaries. I can be in Miami, in Silicon Valley, but I choose Houston for its unlimited resources and talent.” —Jesse Martinez, Investment Partner, Resolved Ventures & Venture Partner, Vamos Ventures Game Changers: The Rise of Sports Tech David Gow, CEO, Gow Media & SportsMap Tech Acquisition Corp. Chris Buckner, CEO, Mainline Lori Burgess, Chief Operating Officer, Beasley Esports Ashley DeWalt, Managing Director, DivInc The booming technology market has expanded to new horizons, including collegiate esports and the advancement in wearable technology. The panel discussed the growth in collegiate esports investments by Houston-based universities like University of St. Thomas and University of Houston. Historically, strong young gamers with elite teams have skipped college and gone directly to pro. “In the next 3-5 years, schools will dive into esports to attract those top-tier students and match the full rides football players are given.” —Lori Burgess, COO, Beasley Esports “Houston is a great home for entrepreneurial innovation. We have an opportunity to create a VC sports tech company that will follow up with all stages to capture and engage a sports tech capital hub.” —David Gow, CEO, Gow Media The Commercial Space Age is Here Dr. Douglas Terrier, Associate Director of Vision & Strategy, NASA - National Aeronautics and Space Administration R. Matt Ondler, CTO, Axiom Space Tim Crain, Chief Technology Officer, Intuitive Machines Arturo Machuca, Director, Ellington Airport and Houston Spaceport (Houston Airport System) With Houston Spaceport’s expansion and improvements, Houston will be the first major metropolitan area in the U.S. to create an environment available to private companies wishing to use a spaceport. The mission is to create a focal point for aerospace innovation with a collection of aerospace companies that will lead the U.S. to transition from government-driven to commercial-driven space programs. “When I think about the Houston Spaceport and think about the summer of 2015 when we got our license, fast-forward a couple years and now we’re building the largest space station--I can just begin to imagine what Houston will bring to the table in the next 5 years.”  -–Dr. Douglas Terrier, Associate Director for Vision and Strategy at NASA’s Johnson Space Center Medtech Transforming Healthcare Industry Joanna Nathan, Manager, New Ventures, Johnson & Johnson Center for Device Innovation James Reinstein, President & CEO, Saranas Inc. Kevin Coker, President & CEO, Proxima Clinical Research, Inc. As home to the largest medical city in the world, Houston is at the forefront of advancing life sciences. Innovation drives collaborations with medicine and cutting-edge technology leveraging resources of enterprises to develop life-saving solutions.  From microbiome engineering to antibiotic resistance, Kevin Coker, President and CEO at Proxima Clinical Research, Inc., commented that, “synthetic biology is going to make a huge difference and cost will decrease in the upcoming years as medical device technology continues to advance. 3D Systems is looking to manufacture the first human organ in East Downtown Houston, so how much more exciting can it get than that?” Accelerating Innovation in Biotech Jason Bock, VP, Biologics Development, MD Anderson Cancer Center Michael Curran, Associate Professor / Founder, MD Anderson Cancer Center / ImmunoGenesis, Inc. Larry Hope, New Ventures and Business Development, MD Anderson Cancer Center The MD Anderson Cancer Center’s panel discussed next-generation cell engineering for tumor infiltrating lymphocyte (TIL) programs. Housing the largest comprehensive cancer center in the U.S., based in Houston, MD Anderson has extensive expertise in developing and manufacturing innovative cell therapies, including groundbreaking work with TILs and setting the proper foundation for biotechnological advancements. “It is my belief that TILs are poised for a significant impact in the field of cancer therapy, and engineering improved TILs is a vital part of advancing this modality.” —Jason Bock, VP, Biologics Development, MD Anderson Cancer Center Click to expand Houston House Panelists. From left: Hossam Elbadawy, Grace Chan, Shawn Cumberland, Vidisha Prasad Day 2: Monday, March 14 Funding the Global Energy Transition Hossam Elbadawy, Managing Director & Technology Partner, SCF Partners Shawn Cumberland, Managing Partner, EnCap Energy Transition Grace Chan, Investment Associate, bp Ventures Vidisha Prasad, Managing Partner, Adya Partners Venture capital experts launched day two of Houston House. Climate change and energy 2.0 have become top priorities for companies with a focus on the hydrogen space. Experts on the panel examined how private and corporate investors continuously seek opportunities in clean technology. “Houston has great resources, including talent, infrastructure, and money, which is what puts Houston at the forefront of the energy transition.” –Grace Chan, Investment Associate at bp Ventures Dream Team: Corporates & Startups in Climatech Andrea Course, Venture Principal, Shell Ventures Dale W., Managing Director, Halliburton Labs Michael W., Senior Investment Manager, Equinor Ventures Dawn James, Director, Global Industry Strategy - Energy & Sustainability, Microsoft The panel explored the collaboration needed for success in the energy transition and voiced consensus that the foundation of corporations with the agility of startups is critical. "It’s true that it’s going to take everybody, this is the ultimate group project.” —Dawn James, Director of Global Industry Strategy - Energy & Sustainability at Microsoft “Particularly in Houston, corporations have the experience, talent, expertise, connections, and facilities that are going to be important to commercialize the technologies of the future.” —Dale Winger, Managing Director, Halliburton Labs Tech Powering the Global Energy Transition Trevor Best, CEO, Syzygy Plasmonics Moji Karimi, CEO, Cemvita Factory Inc. Federico Marques, Founder & CEO, Moonflower Farms Jane Stricker, SVP of Energy Transition and HETI Executive Director, Greater Houston Partnership With the ongoing emergence of energy transition companies in Houston, startups are tackling climate change head on. Comprised of the founders of some of the most promising tech startups, the panel discussed their input in accelerating the global energy transition. “In Houston, we’ve launched The Ion, Halliburton Labs, Greentown Labs, a pretty broad range of incubators creating an ecosystem of innovation just in the last two years that allow for this green energy transition.” —Jane Stricker, Executive Director at HETI “If you’re a climatetech VC and you’re not looking at Houston, Texas, then you’re about to miss out because things are happening in Houston.” —Trevor Best, CEO of Syzygy Plasmonics “If I want Houston to become a bio-manufacturing hub, which I think it could be, the city has done a great amount in showing the vision and the will giving a new generation for companies to grow.” —Moji Karimi, CEO, CemvitaFactory Roadmap to an Equitable Energy Transition John Hall, President and CEO, HARC | Houston Advanced Research Center Dana Harmon, Executive Advisor, Texas Energy Poverty Research Institute Jane Stricker, SVP of Energy Transition and HETI Executive Director, Greater Houston Partnership The panel discussion allowed for an open dialogue on the disparity of the economic and human health outcomes related to climate change.  “Climate change has disproportionately affected low-to-moderate income communities the most, so how do we address the inequities? To remain the nation’s leader in energy, Texas must lean into its abundant renewable energy resources and lead the development and manufacturing of technologies that reduce and eliminate the climate and health pollution emitted by fossil fuels in commerce, industry, and vehicles.” —John Hall, President and CEO, HARC | Houston Advanced Research Center “In some of our recent data, what we’ve seen is people will, basically, self-meter energy consumption in Texas in July, August, September, and we do have evidence of heat exacerbated health effects caused by energy insecurity, so not being able to find cooling stations and things like that. There are important health implications associated with energy use, so we need to think about it holistically.” —Dana Harmon, Executive Advisor, Texas Energy Poverty Research Institute The entire Houston House at SXSW program will be available on demand soon.
Read More
Aerospace & Aviation

SXSW Roll Call: Houston Here!

Houston innovation will make an appearance at this year’s South by Southwest (SXSW) Conference in Austin. For the second year in a row, the Greater Houston Partnership’s Houston House is preparing to showcase Houston leaders and companies accelerating the city’s thriving innovation ecosystem. From record-breaking venture capital activity to the energy transition, the Houston House line up will feature investors, startup founders and industry MVPs. The Thrilling Tech Ecosystem  Home to the largest medical center in the world, Houston’s innovation in life-sciences is a global commitment. This year’s lineup will unite leaders to discuss medical device technologies and the breakthroughs in cell behavior and medicine. The panels MedTech Transforming Healthcare Industry and Accelerating Innovation in Biotech will feature some of the industry’s top talent, highlighting local advancements in biotech reaching the global community. The Bayou City’s competitive tech ecosystem continues to empower the region’s innovation activity and grow the esports sector. The electronic sports phenomenon has earned a spot in this year’s conference with the panel Game Changers: The Rise of Sports Tech. Panelists will dive into the explosive growth of esports, including the opportunities for founders, investors and fans.  HOU to the Moon Dubbed Space City, it’s clear Houston’s space exploration activity remains unrivaled on the national stage. The Houston House panel The Commercial Space Age Is Here will unite distinguished scientists from NASA and private space startups for an insightful discussion on how this cooperation is enabling the next frontier of space exploration. Sustainable, Climate Resilient Houston Following the Partnership’s release of the Houston Energy Transition Initiative, the region’s clean energy innovation has reached new limits and set higher goals. Houston’s ability to transition to clean energy while addressing climate change will continue to position it as a city of the future while remaining the Energy Capital of the World.  This year’s lineup embraces Houston’s role in the global energy transition, powered by executives driving the solutions behind several of the world’s pressing issues. The panels Funding the Global Energy Transition, Dream Team: Corporates & Startups in ClimateTech, and Roadmap to an Equitable Energy Transition will bring together private and corporate investors to discuss the heightened importance of VC in the energy transition space, collaboration advancing low carbon solutions, regulatory deficiencies, and addressing economic inequities caused by climate change. Innovation in energy transition will be the topic of discussion for the panel Tech Powering the Global Energy Transition. The Partnership’s own Senior Vice President of Energy Transition Jane Stricker will be joined by founders from some of the world's most promising energy tech startups to discuss their critical role in accelerating the global energy transition.  Diversity in the Innovation Ecosystem Despite being a critical force in the U.S. economy, diverse entrepreneurs represent a major funding gap. Access to funding remains a tightly guarded gateway to success and it breaks down to a trillion-dollar missed opportunity in the VC space. Houston House’s panel Funding the Next Generation of Diverse Founders will assemble leaders and investors to discuss the key challenges facing diverse entrepreneurs today and the necessary ingredients in building an inclusive innovation ecosystem. Houston's participation at SXSW will culminate with a dynamic networking session hosted by HX Venture Fund Managing Director Sandy Guitar alongside Syzygy Plasmonics CEO Trevor Best. The networking event Meet Houston's Top Tech Founders will unite Houston's top founders, spotlighting innovation and discussing startup funding. Houston House’s return to SXSW in person creates the ideal platform to promote Houston’s position as the most prominent emerging innovation hub in the country. Learn more about Houston’s strengths and see our complete lineup online.
Read More

Related Events


State of the Texas Medical Center

The Greater Houston Partnership invites you to join us at the 2022 State of the Texas Medical Center Event featuring William "Bill" McKeon, President & CEO of the Texas Medical Center (TMC).…

Learn More
Learn More